IV nutrient therapy delivers vitamins, minerals, antioxidants, and therapeutic compounds directly into your bloodstream — bypassing the digestive system entirely and achieving cellular concentrations that oral supplements cannot replicate. Dr. Katherine Ortiz at DNA Wellness and Longevity Institute in Bonita Springs offers 10 physician-supervised IV formulations, each designed for a specific clinical goal — from immune support and NAD+ cellular repair to sports recovery, beauty, and hangover relief.
Why patients choose us
All IV protocols supervised by Dr. Katherine Ortiz, PA-C, Ph.
Intravenous delivery reaches your cells not filtered by digestion
Serving Bonita Springs, Naples, Estero & Fort Myers
Treatment Overview
Physician-Supervised
100% Bioavailabilit
10 Customized Formulations
Bonita Springs, FL
What Is IV Nutrient Therapy?
When you take a vitamin orally, it travels through your digestive system — absorbed partially through the gut lining, processed by the liver, and delivered to your cells at a fraction of the ingested dose. The bioavailability of oral nutrients varies from as low as 10–30% depending on the compound, your gut health, and individual absorption capacity. IV nutrient therapy bypasses this entirely. Nutrients are delivered directly into the bloodstream at 100% bioavailability, reaching therapeutic concentrations in the blood within minutes — concentrations that are simply not achievable through oral supplementation regardless of dose.
This pharmacological difference is clinically significant for specific compounds. Intravenous Vitamin C, for example, achieves plasma concentrations up to 70 times higher than the maximum achievable through oral dosing — concentrations relevant to immune support and antioxidant activity that oral C cannot replicate. NAD+ is poorly absorbed orally and degrades rapidly in the digestive tract; IV delivery ensures it reaches cells intact. Glutathione, the body's primary intracellular antioxidant, is broken down to its amino acid components when taken orally — IV administration delivers it as the complete molecule directly to cells that need it.
At DNA Wellness, IV nutrient therapy is always supervised and administered by Dr. Ortiz's clinical team. Every patient begins with a brief intake assessment before their first session to confirm there are no contraindications — kidney disease, heart failure, or G6PD deficiency (relevant for high-dose Vitamin C) — and to select the most appropriate formulation for their goals. IV sessions typically take 30–60 minutes and are performed in the clinic's comfortable infusion area.
What Is IV Nutrient Therapy

Methylated Vitamin B12 Infusion
Vitamin B12 is essential for neurological function, red blood cell production, DNA synthesis, and energy metabolism — yet deficiency is remarkably common, particularly in adults over 50, those on metformin, vegetarians, and anyone with compromised gut absorption. Our B12 IV uses methylcobalamin (the activated, methylated form) rather than cyanocobalamin — the biologically active form your cells can use immediately without requiring conversion, which is especially relevant for patients with MTHFR gene variants that impair methylation.
Key benefits:
Cognitive support — B12 is critical for myelin sheath maintenance and neurotransmitter synthesis; deficiency directly impairs memory, focus, and mental clarity
Energy production — supports mitochondrial function and red blood cell formation, reducing the fatigue associated with B12 insufficiency
Immune resilience — adequate B12 supports T-cell and NK-cell function; deficiency is associated with impaired immune response
Mood and sleep regulation — B12 is a cofactor in serotonin and melatonin synthesis; insufficiency is linked to mood disturbance and disrupted sleep
Best for: Fatigue, brain fog, mood changes, patients on metformin or PPIs, those with absorption issues or MTHFR variants.

High-Dose Ascorbic Acid Infusion
Intravenous Vitamin C achieves plasma concentrations up to 70 times higher than the maximum possible through oral supplementation — a pharmacological distinction that makes IV C relevant for immune applications, wound healing support, collagen synthesis, and antioxidant protection at a level oral Vitamin C cannot approach. IV Vitamin C is used in integrative oncology support, post-illness recovery, surgical preparation, and skin rejuvenation protocols. It is one of the most evidence-supported components in IV nutrient medicine.
Key benefits:
Immune system support — at high plasma concentrations, Vitamin C exerts direct antiviral and antibacterial effects and significantly upregulates immune cell activity
Collagen synthesis — Vitamin C is a required cofactor for collagen and elastin production; IV delivery supports skin quality, wound healing, and connective tissue health systemically
Antioxidant protection — neutralizes free radicals and regenerates other antioxidants including Vitamin E and glutathione
UV and environmental protection — reduces oxidative damage from sun exposure and environmental stressors at the cellular level
Note: Patients with G6PD deficiency require screening before high-dose Vitamin C — Dr. Ortiz's intake assessment covers this.
Best for: Immune support, pre/post-illness recovery, skin health, collagen support, antioxidant loading.

The Master Antioxidant
Glutathione is the most abundant intracellular antioxidant in the human body — synthesized in every cell but declining measurably with age, chronic illness, oxidative stress, and toxin exposure. It is the primary defense against cellular oxidative damage, a critical component of liver detoxification (Phase II conjugation), and a regulator of immune function and inflammation. Oral glutathione is largely broken down to its component amino acids before reaching cells; IV delivery provides the complete tripeptide directly to cells that need it — making IV the only reliable method of meaningfully raising intracellular glutathione levels acutely.
Key benefits:
Master antioxidant — neutralizes reactive oxygen species across all cell types, protecting mitochondrial DNA and cellular membranes from oxidative damage
Liver detoxification — essential for Phase II liver detox pathways; supports clearance of heavy metals, environmental toxins, alcohol metabolites, and medications
Skin brightening — inhibits tyrosinase, the enzyme driving melanin production; regular IV Glutathione is used for skin tone evening and brightness
Immune regulation — regulates lymphocyte proliferation and NK cell activity; supports both innate and adaptive immune function
Athletic recovery — reduces exercise-induced oxidative stress and muscle inflammation, supporting faster recovery
Best for: Anti-aging protocols, detoxification, skin brightening, athletic recovery, liver support, post-illness recovery.

Metabolic Support Infusion
The Weight Loss IV formulation at DNA Wellness is a metabolic support drip designed to complement an active weight management program — not a standalone weight loss treatment. It combines lipotropic compounds (typically MIC — methionine, inositol, choline) with B vitamins, amino acids, and hydration support to optimize liver fat metabolism, support energy production, regulate appetite signaling, and improve the cellular environment for fat oxidation. It is most effective for patients already working with Dr. Ortiz on a structured weight management protocol.
Key benefits:
Hepatic fat metabolism — lipotropic compounds support liver function in processing and exporting fat, preventing fatty accumulation and supporting metabolic efficiency
Energy support — B vitamins and amino acids support mitochondrial energy production, reducing the fatigue that often accompanies caloric restriction
Appetite and mood regulation — inositol plays a role in insulin signaling and serotonin pathways, supporting mood stability and appetite control during active weight loss
Liver detoxification — choline supports Phase I and II liver detox, improving clearance of metabolic waste during fat mobilization
Best for: Active weight management programs, metabolic support, patients combining with GLP-1 therapy, fatigue during caloric restriction.

Skin, Hair & Nail Rejuvenation Drip
The Ageless Beauty IV is formulated around the nutrient building blocks of skin, hair, and nail quality — delivering biotin, Vitamin C, glutathione, B vitamins, and zinc in therapeutic combination directly to the bloodstream. This formulation supports collagen and keratin synthesis, protects dermal cells from oxidative damage, restores hydration at the cellular level, and addresses the nutritional deficiencies that contribute to dull skin, brittle nails, and hair thinning — particularly relevant for patients managing these concerns alongside hormonal changes.
Key benefits:
Collagen and elastin production — high-dose Vitamin C and zinc are essential cofactors; IV delivery supports skin structural integrity and reduces fine line appearance
Skin hydration — IV fluids restore cellular and dermal hydration at a level topical products and oral hydration cannot replicate for dehydrated tissue
Hair and nail strength — biotin, B vitamins, and zinc support keratin synthesis for stronger, healthier hair shafts and nail beds
Antioxidant protection — Glutathione neutralizes the free radical damage that accelerates visible skin aging from UV, stress, and environmental exposure
Best for: Skin quality and texture, anti-aging aesthetic support, hair and nail concerns, patients post-illness or post-stress depletion.

Rapid Recovery Infusion
The Jet Lag & Fatigue IV is a rapid rehydration and recovery drip for anyone experiencing acute fatigue from travel, schedule disruption, sleep deprivation, or acute physical or mental exertion. It delivers IV fluids, B vitamins (particularly B12 and B-complex for energy metabolism), electrolytes, and Vitamin C in a fast-acting infusion that restores hydration, replenishes depleted cofactors, and supports the circadian rhythm reset that jet lag disrupts. Most patients feel meaningfully better within the infusion session itself.
Key benefits:
Rapid rehydration — IV fluid delivery restores systemic hydration faster and more completely than oral fluid intake following significant dehydration
Energy cofactor replenishment — B vitamins lost through metabolic demand, stress, and disrupted sleep are restored directly at cellular level
Immune support — travel exposes patients to immune challenges; Vitamin C provides immediate antioxidant and immune support
Circadian recovery support — B12 and magnesium play roles in melatonin synthesis and sleep regulation, supporting faster adaptation to time zone changes
Best for: International travel recovery, acute fatigue, sleep deprivation recovery, pre-event energy support, schedule disruption.

Comprehensive Immune Support Drip
The Immune Booster IV is a broad-spectrum immune support formulation containing normal saline, high-dose Vitamin C, Vitamin D, B-complex vitamins, zinc, and glutathione — addressing multiple layers of immune function simultaneously. It is used proactively during periods of high immune demand (cold and flu season, high-stress periods, travel, pre-surgery) and therapeutically during acute illness or post-illness recovery when oral nutrient absorption is compromised and the immune system's nutrient requirements are highest.
Key benefits:
Rapid rehydration — alcohol is a diuretic; IV fluid replacement restores blood volume and cellular hydration faster and more completely than oral intake while nauseated
Electrolyte restoration — replenishes sodium, potassium, and magnesium lost through diuresis and vomiting
Acetaldehyde support — B vitamins (particularly B1, B6, and B12) are cofactors for acetaldehyde breakdown; replenishing them speeds metabolism of this toxic metabolite
Nausea and headache relief — the infusion may include anti-nausea medication (confirm availability with Dr. Ortiz's team) and magnesium for headache support
Best for: Acute hangover recovery, morning-after events, pre-recovery before a demanding day.

Cellular Energy & Longevity Infusion
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell — central to energy metabolism, DNA repair, sirtuin activation (the proteins that regulate cellular aging), and mitochondrial function. NAD+ levels decline by approximately 50% between the ages of 40 and 60, a decline directly linked to the cellular energy deficit, cognitive changes, and accelerated aging that characterize this period. IV NAD+ is the most direct method of restoring intracellular NAD+ levels — oral precursors (NMN, NR) support NAD+ synthesis indirectly but achieve meaningfully lower plasma levels than direct IV administration.
Key benefits:
Accelerated muscle recovery — amino acids provide building blocks for muscle protein synthesis; IV delivery ensures availability at the cellular level without digestive delay
Reduced oxidative stress — high-intensity exercise generates substantial free radical load; Vitamin C and glutathione neutralize this acutely, reducing the inflammatory recovery period
Electrolyte and hydration restoration — intense exercise depletes sodium, potassium, and magnesium through sweat; IV replacement is more complete and faster than oral rehydration
Endurance and performance support — B vitamins and magnesium support mitochondrial energy production, improving training adaptation and reducing perceived fatigue
Best for: Post-competition recovery, high-volume training periods, pre-event preparation, active patients on concurrent peptide or hormone protocols.

Comprehensive Immune Support Drip
The Immune Booster IV is a broad-spectrum immune support formulation containing normal saline, high-dose Vitamin C, Vitamin D, B-complex vitamins, zinc, and glutathione — addressing multiple layers of immune function simultaneously. It is used proactively during periods of high immune demand (cold and flu season, high-stress periods, travel, pre-surgery) and therapeutically during acute illness or post-illness recovery when oral nutrient absorption is compromised and the immune system's nutrient requirements are highest.
Key benefits:
Multi-layer immune activation — Vitamin C, Vitamin D, zinc, and B vitamins each support distinct components of the immune response: innate immunity, lymphocyte function, antibody production, and anti-inflammatory regulation
Antiviral and antibacterial support — high-dose Vitamin C exerts direct antimicrobial effects at IV plasma concentrations not achievable orally
Lymphatic detoxification — glutathione and Vitamin C support lymphatic function and clearance of immune waste products generated during infection
Rapid nutrient delivery during illness — when appetite and absorption are compromised by acute illness, IV delivery ensures therapeutic nutrient levels regardless of gut status
Best for: Cold and flu season, acute illness recovery, pre/post-surgery support, immune vulnerability, high-stress periods, frequent travellers.

Cellular Energy & Longevity Infusion
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell — central to energy metabolism, DNA repair, sirtuin activation (the proteins that regulate cellular aging), and mitochondrial function.
NAD+ levels decline by approximately 50% between the ages of 40 and 60, a decline directly linked to the cellular energy deficit, cognitive changes, and accelerated aging that characterize this period. IV NAD+ is the most direct method of restoring intracellular NAD+ levels — oral precursors (NMN, NR) support NAD+ synthesis indirectly but achieve meaningfully lower plasma levels than direct IV administration.
NAD+ IV therapy is one of the longer infusions offered at the clinic — sessions typically take 2–4 hours as the infusion rate must be controlled to minimize flushing and nausea, which are common at faster rates. Dr. Ortiz's team manages the infusion rate carefully for patient comfort.
Key benefits:
Cellular energy production — NAD+ is required for the electron transport chain in mitochondria; restoring NAD+ levels directly improves cellular ATP production and reduces the energy deficit driving age-related fatigue
DNA repair activation — NAD+ is a required substrate for PARP enzymes that identify and repair DNA strand breaks; adequate NAD+ supports genomic integrity and reduces cellular aging
Sirtuin activation — sirtuins (the "longevity proteins") require NAD+ to function; restoring NAD+ activates these enzymes, which regulate inflammation, metabolic efficiency, and cellular stress response
Cognitive clarity and brain health — neurons are particularly dependent on NAD+ for energy and repair; patients frequently report improved mental clarity, focus, and mood following NAD+ infusions
Addiction and withdrawal support — NAD+ has been studied for its role in neurotransmitter restoration in addiction recovery protocols; this is an emerging application discussed case-by-case with Dr. Ortiz
Best for: Anti-aging and longevity protocols, cognitive support, energy restoration in 40s–60s, metabolic optimization, patients on concurrent peptide or hormone therapy.
Am I a Candidate?
IV nutrient therapy is appropriate for a wide range of patients — but the right formulation depends on your clinical picture. Dr. Ortiz's team conducts a brief intake assessment before your first session to confirm there are no contraindications and to match you with the formulation most relevant to your goals.
You may particularly benefit if you are experiencing:
Chronic fatigue or low energy that persists despite adequate sleep
Frequent illness or a sense that your immune system is underperforming
Brain fog, poor concentration, or memory concerns
Signs of skin aging, hair thinning, or nail brittleness
Active weight management and want metabolic nutritional support
Post-illness recovery where appetite and absorption are compromised
Intense athletic training with incomplete recovery between sessions
Jet lag, travel fatigue, or schedule disruption
Acute hangover requiring rapid rehydration and recovery
Interest in longevity support and cellular energy optimization (NAD+)
Contraindications to discuss with Dr. Ortiz at intake:
Kidney disease (impaired clearance of IV fluids and electrolytes)
Congestive heart failure (fluid volume sensitivity)
G6PD deficiency (relevant for high-dose Vitamin C specifically)
Allergy to any component of the selected formulation
Your Session

Step 01 — Brief Intake & Formulation Selection Your first IV session begins with a brief intake review by Dr. Ortiz's clinical team — confirming your health history, current medications, and goals, and ruling out any contraindications relevant to your selected formulation. For returning patients, this step is a brief check-in. For new patients, it typically takes 10–15 minutes. Dr. Ortiz reviews the clinical rationale for each formulation and guides you to the most appropriate choice if you are unsure — or if your goals suggest a combination of formulations across multiple sessions.
Step 02 — The Infusion Session A small IV catheter is placed in a vein in your arm or hand. The selected nutrient formulation is delivered by IV drip over the course of the session — typically 30–60 minutes for most formulations, and 2–4 hours for NAD+. Most patients find the experience comfortable and restful; many read, work on their phone, or simply relax during the infusion. Mild warmth or a cooling sensation in the arm is normal. The clinical team monitors you throughout the session.
Step 03 — Post-Infusion & Ongoing Support Most patients feel the effects within the session or shortly after — particularly with energy and hydration-focused formulations. Some effects (collagen support, immune modulation, NAD+ cellular repair) develop over days to weeks as the biological response unfolds. Dr. Ortiz recommends session frequency based on your goals: some patients come monthly for maintenance, others weekly during periods of high immune demand or active training. IV therapy integrates well with concurrent hormone optimization, peptide therapy, and PRP protocols at the clinic.
Dr. Katherine Ortiz is the founder of DNA Wellness and Longevity Institute in Bonita Springs, FL. She is a board-certified Physician Associate and holds a Ph.D. in Integrative Medicine from Quantum University, with fellowship training through the American Academy of Anti-Aging Medicine (A4M) and the University of South Florida in functional and regenerative medicine.
Her practice is built on a foundational belief: that the body has an extraordinary capacity to heal and self-regulate when given the right support. Dr. Ortiz investigates root causes — hormonal imbalances, nutritional deficiencies, genetic factors — and builds individualized protocols designed to restore function and optimize long-term health.
Every protocol at DNA Wellness is ordered, reviewed, and monitored directly by Dr. Ortiz.