Peptide Therapy · Bonita Springs, Fl
The Selank & Semax Stack in Bonita Springs, FL
A Two-Peptide Protocol for Stress Resilience & Cognitive Clarity
The Selank & Semax Stack combines two Russian-developed neuropeptides that work on complementary pathways in the brain — one calming the stress response, the other sharpening focus and cognitive performance. Together they support mental clarity without the jitteriness of stimulants or the dulling effect of anti-anxiety medication, in a protocol built and supervised by Dr. Katherine Ortiz.
Why patients choose us
Physician-Led
All protocols supervised by
Dr. Katherine Ortiz I-MD, Ph.D., PA-C, M.M.S., ABAAHP
Systemic Reach
Distributes throughout the body — not limited to one injury site
SW Florida
Serving Bonita Springs, Naples, Estero & Fort Myers
Treatment Overview
Selank & Semax Stack Therapy
Physician-Supervised
Derived from Natural Thymosin Beta-4
Systemic Distribution
Bonita Springs, FL
What Is the Selank & Semax Stack?
Why these two together
Selank — Stress & mood regulation
A synthetic analog of the immune peptide tuftsin, Selank works on GABA and serotonin pathways to reduce anxiety and stabilize mood without sedation, while also showing anti-inflammatory and immune-modulating effects.
Semax — Cognitive performance
A synthetic ACTH fragment that increases BDNF (brain-derived neurotrophic factor) and modulates dopamine and serotonin activity — supporting focus, memory, and mental stamina, particularly under stress or fatigue.
Learn about Semax
Who the Selank & Semax Stack is for
Patients managing chronic stress, mild anxiety, brain fog, or cognitive fatigue who want mental clarity without stimulants or sedatives. Frequently used by professionals managing high-demand workloads, patients in cognitive decline prevention protocols, or as part of a broader longevity and stress-resilience plan.
How It Helps
What are they?
Semax
Semax is a synthetic peptide developed in Russia in the 1980s, derived from a fragment of adrenocorticotropic hormone (ACTH 4-10) with additional amino acids added for stability. It has no hormonal activity itself — the ACTH connection is structural only, not functional.
Its primary mechanism is increasing brain-derived neurotrophic factor (BDNF), a protein that supports neuron growth, survival, and synaptic plasticity. It also modulates dopamine and serotonin turnover in the prefrontal cortex and influences acetylcholine activity, which plays a role in attention and memory formation.
Clinically, it's positioned as a nootropic — used for focus, mental stamina, memory, and recovery from cognitive fatigue. In Russia it has formal approval for conditions like stroke recovery and certain neurological disorders; in a wellness context here, it's typically used off-label for cognitive performance support. It's usually administered intranasally, since it doesn't survive oral digestion well and intranasal delivery allows reasonably direct access toward the central nervous system.
Selank
Selank is a synthetic peptide, also developed in Russia, derived from tuftsin — a naturally occurring immunomodulatory peptide fragment of an antibody (IgG). Like Semax, amino acids were added to extend its stability and half-life.
Its primary mechanism involves the GABAergic system and serotonin pathways — it appears to enhance GABA activity (the brain's main inhibitory, calming neurotransmitter) without causing sedation, and it influences the balance of serotonin and its precursor tryptophan. It also has documented effects on inflammatory cytokine expression, consistent with its immune-peptide origin.
Clinically, it's used for anxiety and mood regulation — described as anxiolytic without the sedation, dependency risk, or cognitive blunting associated with benzodiazepines. It's also studied for stress resilience and has shown some immune-modulating effects in animal research. Like Semax, it's typically delivered intranasally for the same bioavailability reasons.
Your Journey
Common questions
Is this one combined formula or two separate peptides?
Protocols are individualized. Dr. Ortiz determines whether Selank and Semax are dosed together or on a rotating schedule based on your clinical picture and goals.
How are Selank and Semax administered?
Both are most commonly delivered intranasally, making this one of the simplest peptide protocols to self-administer at home between visits.
How long until I notice a difference?
Many patients report subtle shifts in stress response within days, with cognitive benefits typically building over 2–4 weeks of consistent use.
Can I start with just one peptide instead of the full stack?
Yes. Some patients begin with Selank alone for anxiety/mood, or Semax alone for focus, and add the second peptide later based on response.
Meet Dr. Katherine Ortiz
Dr. Katherine Ortiz is the founder of DNA Wellness and Longevity Institute in Bonita Springs, FL. She is a board-certified Physician Associate and holds a Ph.D. in Integrative Medicine from Quantum University, with fellowship training through the American Academy of Anti-Aging Medicine (A4M) and the University of South Florida in functional and regenerative medicine.
Her practice is built on a foundational belief: that the body has an extraordinary capacity to heal and self-regulate when given the right support. Dr. Ortiz investigates root causes — hormonal imbalances, nutritional deficiencies, genetic factors — and builds individualized protocols designed to restore function and optimize long-term health.
Every protocol at DNA Wellness is ordered, reviewed, and monitored directly by Dr. Ortiz.
